11/1/2024

Desmopressin Acetate Nasal Spray

Products Affected - Description

- DDAVP nasal spray, Ferring, 10 mcg/0.1 mL, 5 mL bottle, NDC 55566-2500-00
- Stimate nasal spray, Ferring, 150 mcg/0.1 mL, 2.5 mL bottle, NDC 00053-6871-00
- Desmopressin Acetate nasal spray, Amring Pharmaceuticals, 10 mcg/0.1 mL, 5 mL bottle, NDC 69918-0501-05 - discontinued
- Desmopressin Acetate nasal spray, Sun Pharma, 10 mcg/0.1 mL, 5 mL bottle, NDC 47335-0788-91 - discontinued
- Desmopressin Acetate nasal spray, Zydus, 10 mcg/0.1 mL, 5 mL bottle, NDC 68382-0384-01 - discontinued

Reason for the Shortage

- Amring has discontinued desmopressin nasal spray.
- Apotex has desmopressin nasal spray available.
- Bausch Health has desmopressin acetate nasal spray available.
- Ferring has desmopressin nasal spray on shortage due to packaging issues.

Available Products

- Desmopressin Acetate nasal spray, Apotex, 10 mcg/0.1 mL, 5 mL bottle, NDC 60505-0815-00
- Desmopressin Acetate nasal spray, Bausch Health, 10 mcg/0.1 mL, 5 mL bottle, NDC 24208-0342-05

Estimated Resupply Dates

- Ferring has Stimate nasal spray on back order and the company cannot estimate a release date.
- Ferring has DDAVP nasal spray on back order and the company cannot estimate a release date.

Implications for Patient Care

- Stimate contains a higher concentration of desmopressin per spray (150 mcg/actuation) than other desmopressin nasal spray products. It is approved for use in hemophilia A and in mild to moderate Type I von Willebrand's disease with Factor VIII levels greater than 5%.[1]
- Desmopressin nasal spray 10 mcg/actuation is labeled for use as antidiuretic replacement therapy in the management of central diabetes insipidus in adults and children 4 years of age and older.[1]

References

1. Desmopressin. Lexi-Drugs Online. Hudson, OH: Lexi-Comp Inc; 2020.

Updated

Updated November 1, 2024 by Leslie Jensen, PharmD, Drug Information Specialist. Created August 14, 2020 by Leslie Jensen, PharmD, Drug Information Specialist. © 2024, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

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