11/22/2024

Alteplase Injection

Products Affected - Description

- Activase intravenous lyophilized powder for injection, Genentech, 100 mg, kit, 1 count, NDC 50242-0065-27

Reason for the Shortage

- Genentech did not provide a reason for the shortage of Activase 100 mg kits. The 50 mg kits are available.

Available Products

- Activase intravenous lyophilized powder for injection, Genentech, 50 mg, kit, 1 count, NDC 50242-0044-13

Estimated Resupply Dates

- Genentech has Activase 100 mg kits on intermittent back order and the company is releasing supplies as they become available.

Alternative Agents & Management

- Genentech has issued a Dear Healthcare Provider letter which provides instructions on how to prepare a dose over 50 mg using Activase 50 mg vials. The Dear Healthcare Provider letter can be found at https://www.gene.com/download/pdf/Activase_DHCP_Important-Prescribing-Information_11-14-24.pdf. The full instructions for alternate dose preparation can be found at :https://www.gene.com/download/pdf/activase_instructions_for_alternate_preparation.pdf.

Updated

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