11/4/2024

Levofloxacin Injection in 5% Dextrose

Products Affected - Description

- Levofloxacin in 5% Dextrose intravenous solution for injection, Baxter, 250 mg/50 mL, flexible container, 24 count, NDC 36000-0046-24 - discontinued
- Levofloxacin in 5% Dextrose intravenous solution for injection, Baxter, 500 mg/100 mL, flexible container, 24 count, NDC 36000-0047-24 - discontinued
- Levofloxacin in 5% Dextrose intravenous solution for injection, Baxter, 750 mg/150 mL, flexible container, 24 count, NDC 36000-0048-24 - discontinued
- Levofloxacin in 5% Dextrose intravenous solution for injection, Hikma, 250 mg/50 mL, flexible container, 24 count, NDC 00143-9722-24
- Levofloxacin in 5% Dextrose intravenous solution for injection, Hikma, 500 mg/100 mL, flexible container, 24 count, NDC 00143-9721-24
- Levofloxacin in 5% Dextrose intravenous solution for injection, Hikma, 750 mg/150 mL, flexible container, 24 count, NDC 00143-9720-24
- Levofloxacin in 5% Dextrose intravenous solution for injection, Pfizer, 250 mg/50 mL, flexible container, 24 count, NDC 00409-0528-15
- Levofloxacin in 5% Dextrose intravenous solution for injection, Pfizer, 500 mg/100 mL, flexible container, 24 count, NDC 00409-0528-25
- Levofloxacin in 5% Dextrose intravenous solution for injection, Pfizer, 750 mg/150 mL, flexible container, 24 count, NDC 00409-0528-35
- Levofloxacin in 5% Dextrose intravenous solution for injection, Sagent, 250 mg/50 mL, flexible container, 24 count, NDC 25021-0132-81
- Levofloxacin in 5% Dextrose intravenous solution for injection, Sagent, 500 mg/100 mL, flexible container, 24 count, NDC 25021-0132-82
- Levofloxacin in 5% Dextrose intravenous solution for injection, Sagent, 750 mg/150 mL, flexible container, 24 count, NDC 25021-0132-83
- Levofloxacin in 5% Dextrose intravenous solution for injection, WG Critical Care, 500 mg/100 mL, flexible container, 24 count, NDC 44567-0436-24
- Levofloxacin in 5% Dextrose intravenous solution for injection, WG Critical Care, 750 mg/150 mL, flexible container, 24 count, NDC 44567-0437-24

Reason for the Shortage

- Baxter has discontinued levofloxacin premixed bags. The 750 mg/150 mL premixed bags inventory is depleted. The 250 mg/50 mL and 500 mg/100 mL premixed bags are available until remaining inventory is depleted.
- Hikma did not provide a reason for the shortage.
- Pfizer states the shortage is due to a manufacturing delay.
- Sagent did not provide a reason for the shortage.
- WG Critical Care did not provide a reason for the shortage.

Available Products

- Levofloxacin in 5% Dextrose intravenous solution for injection, WG Critical Care, 250 mg/50 mL, flexible container, 24 count, NDC 44567-0435-24

Estimated Resupply Dates

- Hikma has levofloxacin 500 mg/100 mL and 750 mg/150 mL premixed bags on back order and the company estimates a release date of mid-November 2024 for the 500 mg/100 mL bags and early-November 2024 for the 750 mg/150 mL premixed bags. The 250 mg/50 mL premixed bags are on back order and the company cannot estimate a release date.
- Pfizer has levofloxacin 250 mg/50 mL, 500 mg/100 mL, and 750 mg/150 mL premixed bags on back order and the company estimates a release date of December 2027.
- Sagent has levofloxacin 750 mg/150 mL on back order and the company estimates a release date of October 2024. The 250 mg/50 mL premixed bags are on limited allocation. The 500 mg/100 mL premixed bags are short-dated (December 2024).
- WG Critical Care has levofloxacin 500 mg/100 mL premixed bags on back order and the company cannot estimate a release date. Levofloxacin 750 mg/150 mL bags are on back order and the company estimates a release date of early-December 2024.

Updated

Updated November 4, 2024 by Leslie Jensen, PharmD, Drug Information Specialist. Created May 29, 2024 by Leslie Jensen, PharmD, Drug Information Specialist. © 2024, Drug Information Service, University of Utah, Salt Lake City, UT.

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